DRUG SPOTLIGHT …… DOXOFYLLINE

New Drug Approvals

DOXOFYLLINE

LAUNCHED 1987, Istituto Biologico Chemioterapico ABC

69975-86-6  CAS NO

7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione

1H-Purine-2,6-dione, 3,7-dihydro-7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethyl- (9CI)

7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 7-[1,3-(Dioxolan-d4)-2-ylmethyl)]theophylline; 2-(7�-Theophyllinemethyl)-1,3- dioxolane; ABC 12/3; ABC 1213; Ansimar; Dioxyfilline; Doxophylline; Maxivent; Ventax;

Synonyms

  • 2-(7′-Teofillinmetil)-1,3-diossolano
  • 2-(7′-Teofillinmetil)-1,3-diossolano [Italian]
  • 2-(7′-Theophyllinemethyl)-1,3-dioxolane
  • 5-26-14-00120 (Beilstein Handbook Reference)
  • 7-(1,3-Dioxolan-2-ylmethyl)theophylline
Formula C11H14N4O4 
Mol. mass 266.25 g/mol
  • ABC 12/3
  • Ansimar
  • BRN 0561195
  • Dioxyfilline
  • Doxofilina
  • Doxofilina [INN-Spanish]
  • Doxofylline
  • Doxofyllinum
  • Doxofyllinum [INN-Latin]
  • Doxophylline
  • EINECS 274-239-6
  • Maxivent
  • UNII-MPM23GMO7Z
  • Ventax

Doxofylline (INN), (also known as doxophylline) is a xanthine derivative drug used in the treatment of asthma.[1]

Doxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases

It has antitussive and bronchodilator[2] effects, and acts as aphosphodiesterase inhibitor.[3]

In animal and human studies, it…

View original post 2,080 more words

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s