New Drug Approvals


LAUNCHED 1987, Istituto Biologico Chemioterapico ABC

69975-86-6  CAS NO


1H-Purine-2,6-dione, 3,7-dihydro-7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethyl- (9CI)

7-(1,3-Dioxolan-2-ylmethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 7-[1,3-(Dioxolan-d4)-2-ylmethyl)]theophylline; 2-(7�-Theophyllinemethyl)-1,3- dioxolane; ABC 12/3; ABC 1213; Ansimar; Dioxyfilline; Doxophylline; Maxivent; Ventax;


  • 2-(7′-Teofillinmetil)-1,3-diossolano
  • 2-(7′-Teofillinmetil)-1,3-diossolano [Italian]
  • 2-(7′-Theophyllinemethyl)-1,3-dioxolane
  • 5-26-14-00120 (Beilstein Handbook Reference)
  • 7-(1,3-Dioxolan-2-ylmethyl)theophylline
Formula C11H14N4O4 
Mol. mass 266.25 g/mol
  • ABC 12/3
  • Ansimar
  • BRN 0561195
  • Dioxyfilline
  • Doxofilina
  • Doxofilina [INN-Spanish]
  • Doxofylline
  • Doxofyllinum
  • Doxofyllinum [INN-Latin]
  • Doxophylline
  • EINECS 274-239-6
  • Maxivent
  • Ventax

Doxofylline (INN), (also known as doxophylline) is a xanthine derivative drug used in the treatment of asthma.[1]

Doxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases

It has antitussive and bronchodilator[2] effects, and acts as aphosphodiesterase inhibitor.[3]

In animal and human studies, it…

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